The 2025 Audi A5, S5, and RS 5 lineup is offered in coupe, cabriolet, and Sportback body styles. The all-new A5 features a 2.0L TFSI turbocharged four-cylinder engine with a hybrid system, producing 268 horsepower. A5 Sportback 40 models deliver 201 horsepower. The S5 models receive a 3.0L turbocharged TFSI V6 generating 349 horsepower and 369 lb-ft of torque. For maximum performance, the RS 5 employs a 2.9L twin-turbo V6 developing 444 horsepower and 443 lb-ft of torque. All variants come equipped with Audi's Quattro all-wheel drive system.

Transmission options vary across the model range. The A5 Sportback, Cabriolet, and Coupe utilize a 7-speed dual-clutch automatic transmission. The S5 and RS 5 models feature an 8-speed Tiptronic automatic transmission with four distinct driving modes (Comfort, Auto, Dynamic, and Individual).

Trim levels for A5 and S5 models include Premium, Premium Plus, and Prestige. Standard equipment on Premium models includes a panoramic sunroof, 10.1-inch MIB 3 infotainment system, heated power mirrors, rain-sensing wipers, 10-speaker audio system, heated windshield nozzles, leather upholstery, power front seats, push-button start, 3-zone automatic climate control, wireless smartphone integration, and a 180-watt sound system. S5 Premium models feature 19-inch aluminum wheels and leather/Dinamica upholstery with diamond stitching.

The top-tier RS 5 features 19-inch forged aluminum wheels, the premium Bang & Olufsen sound system, leather power seats with massage function, sport rear differential, and a twin-turbo V6 powerplant.

Standard safety features include front and rear parking sensors, active lane departure, forward collision mitigation and a front pedestrian detection system.